Now that you know about the immune response, return to the article .dartmouth.edu/fall-2010/the-physiology-of-stress-cortisol-and-the-hypothalamic-pituitary-adrenal-axis#.U-aGCONdVyw”>The Physiology of Stress: Cortisol and the Hypothalamic-Pituitary-Adrenal Axis in the Dartmouth Undergraduate Journal of Science and read the section related to the immune system in closer detail. Using this as a starting point, complete the requirements below using paragraph format to address each topic:
Paragraph 1: Introduction
Note that the inflammatory response and the complement system are mentioned in the article. Now learn more about the .pearsoncustom.com/mct-comprehensive/asset.php?isbn=1269879944&id=8622″>inflammatory response and the .pearsoncustom.com/mct-comprehensive/asset.php?isbn=1269879944&id=8631″>inflammatory mediators. You will find information on the .pearsoncustom.com/mct-comprehensive/asset.php?isbn=1269879944&id=8600″>complement system as well. Do a little research on these components and provide a paragraph explaining the normal function and steps associated with signaling these components. Identify where in this cascade of signaling events that cortisol is thought to interfere.
Paragraph 2: PTSD and the Complement System
Now compare the theory mentioned in the Dartmouth article to the findings in this study on .ncbi.nlm.nih.gov/pmc/articles/PMC2834673/”>PTSD and the complement system. Focus on the Abstract and Discussion sections of this study on PTSD. Address the following questions:
What did they find in common among PTSD patients?
How does alteration of the complement affect the inflammatory response?
Paragraph 3: Inflammatory
Response and the Brain
Finally, read .dana.org/Publications/ReportOnProgress/Consequences_of_the_Inflamed_Brain/”>The Consequences of the Inflamed Brain and draw connections between the inflammatory response and brain function and behavior. How are the CNS and the immune system interconnected? How does the inflammatory response affect mood and behavior?
Which component of the nervous system reacts to an infection? What are the implications for mood and behavior if the inflammatory response is prolonged? What types of things might cause the inflammatory response to become prolonged or exaggerated?
Paragraph 4: Conclusions
To complete this assignment, “connect the dots” between the influence of stress on the immune system, the potential effects that PTSD can have on the inflammatory response (remember this occurs after an extremely stressful event and is related to dysregulation of cortisol), and the perpetuation of depression and other symptoms of PTSD.
You are provided with many scholarly references to complete this assignment. Include a References section that lists these and any additional sources you used (refer to the Background page). For any additional research you are required to do to complete your assignment, please use scholarly references such as a peer-reviewed journal article or a government-sponsored or university-sponsored website. As you read through your sources, take notes from your sources and then write your paper in your own words, describing what you have learned from your research. Direct quotes should be limited and must be designated by quotation marks. Paraphrased ideas must give credit to the original author, for example (Murray, 2014). Direct copying from “homework help” websites will not receive credit.
For this Case Assignment, answer all questions using full sentences and use the headings provided above to organize your paper.
You must complete your Case 3 assignment before you can proceed with this assignment.
In this module’s SLP assignment, you will take a break from the anatomy and physiology of stress to analyze the work you have done so far, specifically in your Module 3 Case Assignment.
The readings you accomplished for Module 3’s Case Assignment are quite new scientific theories that are currently being tested by scientists who are trying to figure out why individuals suffer from behavioral issues such as depression and PTSD. The scientific and medical communities have collected a lot of evidence that stress plays a very big role in not only creating these behaviors, but also perpetuating them. We still have a long way to go and a lot of unanswered questions!
By completing Case 3, you have participated in the .pearsoncustom.com/mct-comprehensive/asset.php?isbn=1269879944&id=10647″>scientific method. After you view this linked animation, use this .pearsoncustom.com/mct-comprehensive/asset.php?isbn=1269879944&id=5624″>diagram as your reference point to complete the following components of this assignment:
In which part of the Case Assignment did you address Step 1, “observe and generalize”?
Which part of the Case Assignment required you to accomplish Step 2, “formulate a hypothesis”?
Did your hypothesis contain information that can be accepted as the absolute truth? If not, what information was missing? (HINT: Think back to the studies about cortisol and PTSD.) Based on the information that was missing from your hypothesis, what could you test in order to obtain more information on the unknown piece?
Do a bit of research on the technology available today that could facilitate this test. Examples of new technology include brain imaging, blood chemistry and hormone level tests, CAT scans, MRIs, and DNA mapping. What step of the scientific method does this require?
Now that you have some additional information, briefly and in simple terms, describe how you would test the missing information and which step of the scientific method this accomplishes.
SLP Assignment Expectations
For this SLP assignment, answer all questions using full sentences in paragraph format. For any additional research you are required to do to complete your assignment, please use scholarly references such as a peer reviewed journal article or a government sponsored or university sponsored website. As you read through your sources, take notes from your sources and then write your paper in your own words, describing what you have learned from your research. Direct quotes should be limited and must be designated by quotation marks. Paraphrased ideas must give credit to the original author, for example (Murray, 2014). Direct copying from “homework help” websites will not receive credit.
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